Thornton Manor can be found centrally located on the Wirral Peninsula - Manor Road, Thornton Hough, CH63 1JB. The manor is a few minutes drive from Junction 4 of the M53 and the main entrance is marked by a grand Tudor Revival gatehouse.

Train stations within the vicinity primarily serve local destinations, however Liverpool city centre and various hotel options are approximately 20 minutes driving distance.

Thornton Manor does itself have some accommodation, however this is limited and available on a first come first served basis. Within a 5 minute drive of Thornton Manor alternative accommodation options include Thornton Hall (not to be confused!) and Premier Inn Heswall.